lipid nanoparticle

In recent years, mRNA has attracted much attention as a multifunctional therapeutic agent, and it has the potential to prevent and treat various diseases. Current clinical work is focused on vaccination, protein replacement therapy, and the treatment of genetic diseases. Through the development of mRNA production design and intracellular delivery methods, clinical translation of mRNA therapeutics has become possible. Studies have shown that a class of lipid-like substances (called lipidoids) is formulated into lipid nanoparticles (LNPs), which can effectively deliver a variety of nucleic acids in vivo and in vitro.

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